Starting November 16, 2024 until May 31, 2025, the TRLM NG application will be undergoing system maintenance and may be intermittently unavailable from Saturday 9AM EDT to Sunday 6PM EDT. If you have additional questions, please email CTP-TRLM-NG-Helpdesk@fda.hhs.gov. The TRLM NG Help Desk is available Monday-Friday between 9:00AM – 8:00PM EDT.

Notice: New legislation enacted on March 15, 2022, makes clear that FDA has the authority to regulate tobacco products containing nicotine from any source, including synthetic nicotine. The changes to the law take effect April 14, 2022.

Manufacturers of tobacco products containing nicotine not derived from tobacco (NTN) must ensure compliance with applicable requirements under the FD&C Act resulting from this law, such as:

  • Register with FDA and list all NTN products that they manufacture, prepare, compound, or process for commercial distribution

    Please see the CTP Newsroom announcement.

  • Establishment Registration & Tobacco Product Listing

    This database is refreshed daily to include product listings & tobacco establishments registered through the FDA. To view this information, navigate to the links provided below.

    • Tobacco establishments registered with FDA; and
    • Tobacco products listed with FDA.

    Note: Registration of an establishment, assignment of an FDA Establishment Identifier (FEI) number, or listing of a product does not constitute a jurisdictional determination, or an agency review or determination that the establishment or product is in compliance with FDA regulator


    Registration and listing information is provided and periodically updated by regulated entities. FDA has posted the submitted information publicly as a means of providing public access to the information, which is required by Section 905(f) of the Tobacco Control Act, and as a service to interested stakeholders. FDA is not vouching for the accuracy of any particular entry, because it is posting the information as received, nor can it prevent the submission of duplicate, inaccurate, and/or unnecessary entries. Further, since the data is regularly updated by regulated entities, it is also unstable due to significant changes from month to month. FDA is currently working to assess the registration and listing information filed by regulated entities, including the information displayed here, and to establish a path toward improving the accuracy, completeness, and reliability of this information. At this time, FDA cautions those accessing the tobacco registration and product listings to recognize the limitations described above related to the completeness and accuracy of the information.